CBDA (cannabidiolic acid) is the main cannabinoid that CBD and THC are derived. CBDA converts into either THC or CBD depending on the plant enzymes that are activated. CBDA converts to CBD when decarboxylation occurs as the plant is exposed to either sunlight or heat. CBDA is the raw form of CBD and is available in topicals, tinctures, capsules, or other forms. CBDA interacts with the endocannabinoid system, although not in the traditional way that cannabinoids bind with CB1 or CB2 receptors. CBDA inhibits the cyclooxygenase-2 (COX-2) enzyme, which is associated with inflammation thus, CBDA can alleviate inflammation by blocking the COX-2 enzyme. Many studies report the effectiveness of CBDA in treating many conditions and report an even greater treatment for seizures than CBD. More research is needed to realize the full potential of this motherload of a cannabinoid.